However, human studies are limited ( 1, 2).Ī yearlong study gave 130 women with breast cancer on tamoxifen therapy either a placebo or 150 mg of DIM twice a day. Test-tube and animal studies suggest that DIM supplements may help prevent the growth and spread of breast cancer cells. While these benefits are promising, overall research on DIM’s effectiveness and long-term safety in humans is limited. They’re also used to help prevent prostate enlargement, treat acne, aid weight loss, and reduce premenstrual syndrome (PMS) and menopause symptoms. Uses and potential benefits of DIM supplementsĭIM supplements are being studied for their protective effects against certain cancers. While more research is needed, it’s thought to help balance hormone levels via its effects on estrogen. SummaryĭIM is a compound your body makes from cruciferous vegetables. While cruciferous vegetables are the primary food source of DIM, you would need to eat several servings every day to reap this compound’s benefits ( 1).Īs a result, people looking to treat a specific condition like acne or prostate issues may seek a concentrated dose in the form of a DIM supplement. It may also help reduce the effects of a stronger form called 16 alpha-hydroxyestrone, which has been linked to weight gain and an increased risk of some cancers, including breast and uterine cancer ( 1, 7).Īdditionally, DIM has been shown to inhibit an enzyme called aromatase, which converts testosterone to estrogen ( 1). Specifically, DIM may stimulate the production of a less potent, more beneficial form of estrogen known as 2-hydroxyestrone ( 1). While the exact mechanism is unknown, indole-3-carbinol is thought to be partly responsible ( 4, 5, 6).Īlthough research on DIM is still quite limited, it’s thought to help balance estrogen levels in your body ( 1). Intriguingly, observational studies associate high cruciferous vegetable intake with a reduced risk of certain cancers, including breast and prostate cancer. If making a post asking for the easy way out on learning about a compound, most likely you will just be linked to as it is less work for us.īe sure to read the /r/fitness/wiki/faq if your post is about diet/fat loss/gaining muscle.When you eat cruciferous vegetables, your stomach acid breaks down a compound called indole-3-carbinol to produce a new compound called DIM ( 3). Prior to posting, please review the compound on a science-based website like rather than asking for vague 'educate me on.' posts. If you make a claim about a supplement and get called out on it be prepared to either cite your source or logically defend your stance.īroscience is accepted as it can lead to new theories and discoveries, but it must be clearly stated it is broscience or 'feel'. Although subjective, any posts in which there is suspicion of being affiliated with a supplement company may result in banning after various considerations (contribution to community, relevance to discussion, unforeseen context, etc.) are looked at. It is acceptable to talk about which companies and suppliers you like but unacceptable to spam for them. (Basically, talk with us about something don't be a pretentious anti-supplement douche)Īnything talking about supplement companies is a grey area which must be ventured cautiously. Repeated offenses or notably excessive offenses are subject to banning. However, discussions or rants declaring a supplement or supplement regimen useless based on emotion and naturalistic fallacy rather than science or logical caution are subject to moderation. Discussion on the relative pros and cons for supplementation are accepted and encouraged. This is a subreddit designed for supplements, so obviously most users will be biased for supplements. This is to help reduce spamming in the subreddit if you wish to discuss your brand name supplement, simply list the ingredients and dosages, not the brand name. Posts made with brand name products as the topic of discussion (rather than the molecule(s) in question) may be removed.General Rules and Guidelines or /r/supplements: Slightly more IMPORTANT: In regards to illegal/dangerous drugs and how to approach their mention in this subreddit IMPORTANT: For those with blogs/channels dealing with supplements or members of companies which sell nutritional supplements. A subreddit designed for discussion of supplements and nutraceuticals for health, performance, or any intended (or not intended) purpose.
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